Details of the Drug

General Information of Drug (ID: DM6GFRP)

Drug Name

N-(4-iodophenyl)-4-(trifluoromethoxy)benzamide

Synonyms

CHEMBL252013; N-(4-iodophenyl)-4-(trifluoromethoxy)benzamide; AC1OW6PA

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

407.13

Logarithm of the Partition Coefficient (xlogp)

4.9

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

5

Chemical Identifiers

Formula: C14H9F3INO2
IUPAC Name: N-(4-iodophenyl)-4-(trifluoromethoxy)benzamide
Canonical SMILES: C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)I)OC(F)(F)F
InChI: InChI=1S/C14H9F3INO2/c15-14(16,17)21-12-7-1-9(2-8-12)13(20)19-11-5-3-10(18)4-6-11/h1-8H,(H,19,20)
InChIKey: IUHUCVXLTXIWPU-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transient receptor potential cation channel V1 (TRPV1)	TTMI6F5	TRPV1_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Synthesis of benzamide derivatives as TRPV1 antagonists. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1072-8.