Details of the Drug

General Information of Drug (ID: DM740BS)

Drug Name

BI 1358894

Indication

Disease Entry	ICD 11	Status	REF
Depression	6A70-6A7Z	Phase 2	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Short transient receptor potential channel 4 (TRPC4)	TTX0H5W	TRPC4_HUMAN	Inhibitor	[2]
Short transient receptor potential channel 5 (TRPC5)	TT32NQ1	TRPC5_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT04423757) A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Boehringer Ingelheim.