Details of the Drug

General Information of Drug (ID: DM7AW0X)

• Drug Name: Pyridoxyl-N,O-Cycloserylamide-5-Monophosphate
• Synonyms: [5-hydroxy-6-methyl-4-[[(3-oxo-1,2-oxazolidin-4-yl)amino]methyl]pyridin-3-yl]methyl dihydrogen phosphate; (5-hydroxy-6-methyl-4-{[(3-oxo-1,2-oxazolidin-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate; AC1L1ESQ; PYRIDOXYL-N,O-CYCLOSERYLAMIDE-5-MONOPHOSPHATE; CTK7H6662; L-PYRIDOXYL-N,O-CYCLOSERYLAMIDE-5-MONOPHOSPHATE; L-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE; [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE; Phosphoric acid [4-[[(3-o

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 333.23
  Logarithm of the Partition Coefficient (xlogp); -4.8
  Rotatable Bond Count (rotbonds); 6
  Hydrogen Bond Donor Count (hbonddonor); 5
  Hydrogen Bond Acceptor Count (hbondacc); 9
• Chemical Identifiers:
  Formula: C11H16N3O7P
  IUPAC Name: [5-hydroxy-6-methyl-4-[[(3-oxo-1,2-oxazolidin-4-yl)amino]methyl]pyridin-3-yl]methyl dihydrogen phosphate
  Canonical SMILES: CC1=NC=C(C(=C1O)CNC2CONC2=O)COP(=O)(O)O
  InChI: InChI=1S/C11H16N3O7P/c1-6-10(15)8(3-13-9-5-20-14-11(9)16)7(2-12-6)4-21-22(17,18)19/h2,9,13,15H,3-5H2,1H3,(H,14,16)(H2,17,18,19)
  InChIKey: NNRZSZJOQKAGTO-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 2931
  TTD ID: D02XZI

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mycobacterium Biosynthetic alanine racemase (MycB alr)	TT6TMZU	ALR_MYCSM	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.