Details of the Drug

General Information of Drug (ID: DM7BN5W)

Drug Name

LPN023

Indication

Disease Entry	ICD 11	Status	REF
IgA nephropathy	MF8Y	Phase 2	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

IgA nephropathy

ICD Disease Classification

MF8Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Complement factor B (CFB)	DTT	CFB	1.63E-02	0.07	0.13

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT03373461) Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation. U.S. National Institutes of Health.
2	Complement Inhibitors in Clinical Trials for Glomerular Diseases. Front Immunol. 2019 Sep 27;10:2166.