Details of the Drug

General Information of Drug (ID: DM7NKRO)

Drug Name
ISIS 23559
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
ACATTGCTGCCCTTTGTC
Cross-matching ID
TTD ID
D06UNC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
IKKA messenger RNA (IKKA mRNA) TT1F8OQ IKKA_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 US patent application no. 6,395,545, Antisense modulation of inhibitor-kappa B kinase-alpha expression.
2 Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.
3 Novel IKK inhibitors: beta-carbolines. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2419-22.