General Information of Drug (ID: DM7RNKM)

Drug Name
AMT-060
Synonyms AAV gene therapy (hemophilia B), Amsterdam Molecular Therapeutics/St Jude
Indication
Disease Entry ICD 11 Status REF
Factor IX deficiency 3B11 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0A9PW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor IX (F9) TTFEZ5Q FA9_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Factor IX deficiency
ICD Disease Classification 3B11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor IX (F9) DTT F9 5.69E-01 -0.13 -0.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026919)
2 Phase I/II clinical trial of AMT-060 for treating hemophilia B. uniQure N.V.