Details of the Drug

General Information of Drug (ID: DM7SA9J)

Drug Name

IR-103

Synonyms

HIV vaccine + Amplivax, IRC; HIV vaccine + Amplivax, Immune Response Corp; HIV vaccine + HYB-2055, IRC; HIV vaccine + HYB-2055, Immune Response Corp; Vaccine (HIV) + Amplivax, IRC; Vaccine (HIV) + Amplivax, Immune Response Corp; Vaccine (HIV) + HYB-2055, IRC; Vaccine (HIV) + HYB-2055, Immune Response Corp

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Discontinued in Phase 3	[1]
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Drug Type

Vaccine

Cross-matching ID

TTD ID: D03GAI

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Toll-like receptor 9 (TLR9)	TTSHG0T	TLR9_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Human immunodeficiency virus infection

ICD Disease Classification

1C62

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 9 (TLR9)	DTT	TLR9	2.58E-01	-0.06	-0.17

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019204)
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1759).