Details of the Drug

General Information of Drug (ID: DM7SAKN)

Drug Name

Rostaporfin

Synonyms

Photrex; Purlytin; Rostaporfine; Tin ethyl etiopurpurin dichloride; Tin etiopurpurin dichloride; Photopoint SnET2; SnET2; PNU-167524; PNU-524-OPT-0065

Indication

Disease Entry	ICD 11	Status	REF
Macular degeneration	9B78.3	Phase 3	[1]
Breast cancer	2C60-2C65	Phase 2	[2]
Basal cell carcinoma	2C32	Phase 1	[2]
Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C37H42Cl2N4O2Sn
Canonical SMILES: CCC1=C(C2=CC3=C(C(=C4N3[Sn](N5C(=CC1=N2)C(C6(C5=C(C=C6C(=O)OCC)C7=NC(=C4)C(=C7C)CC)CC)C)(Cl)Cl)C)CC)C
InChI: 1S/C37H43N4O2.2ClH.Sn/c1-10-23-19(6)29-17-33-25(12-3)21(8)34(40-33)26-15-27(36(42)43-14-5)37(13-4)22(9)30(41-35(26)37)18-32-24(11-2)20(7)28(39-32)16-31(23)38-29;;;/h15-18,22H,10-14H2,1-9H3,(H-,38,39,40,41,42);2*1H;/q-1;;;+4/p-3/t22-,37+;;;/m0.../s1
InChIKey: MCTOGTBIQBEIBZ-RHJKTMSGSA-K

Cross-matching ID

PubChem CID: 71306999
TTD ID: D03RQW

Repurposed Drugs (RPD)

Click to Jump to the Detailed RPD Information of This Drug

References

1	ClinicalTrials.gov (NCT00157976) Double-Masked Study of Photrex (Rostaporfin) Photodynamic Therapy in the Treatment of Age-Related Macular Degeneration. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)