Details of the Drug

General Information of Drug (ID: DM892JF)

Drug Name

Alpha-methyl-alpha-phenylsuccinimide (MPS)

Synonyms

2-Methyl-2-phenylsuccinimide; 1497-17-2; 3-methyl-3-phenylpyrrolidine-2,5-dione; alpha-Methyl-alpha-phenylsuccinimide; N-Desmethylmethsuximide; Normesuximide; 2,5-Pyrrolidinedione, 3-methyl-3-phenyl-; a-methyl-a-phenylsuccinimide; N-Demethylmethsuximide; UDESUGJZUFALAM-UHFFFAOYSA-N; 3-Methyl-3-phenyl-2,5-pyrrolidinedione; .alpha.-Methyl-.alpha.-phenylsuccinimide; Normethsuximide; N-Normethsuximide; Desmethylmethsuximide; EINECS 216-091-7; Mesuximide, M(nor-); AC1Q6LV6; AC1L3NJ7; SCHEMBL1568276; UDESUGJZUFALAM-UHFFFAOYSA-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

189.21

Logarithm of the Partition Coefficient (xlogp)

1

Rotatable Bond Count (rotbonds)

1

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

2

Chemical Identifiers

Formula: C11H11NO2
IUPAC Name: 3-methyl-3-phenylpyrrolidine-2,5-dione
Canonical SMILES: CC1(CC(=O)NC1=O)C2=CC=CC=C2
InChI: InChI=1S/C11H11NO2/c1-11(7-9(13)12-10(11)14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13,14)
InChIKey: UDESUGJZUFALAM-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 92154
CAS Number: 1497-17-2
TTD ID: D0A4DR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Voltage-gated calcium channel alpha Cav3.1 (CACNA1G)	TT729IR	CAC1G_HUMAN	Blocker	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32.