Details of the Drug

General Information of Drug (ID: DM8K7CN)

Drug Name
SPK-8011
Indication
Disease Entry ICD 11 Status REF
Haemophilia A 3B10.0 Phase 1/2 [1]
Drug Type
Gene therapy
Cross-matching ID
TTD ID
DW7PT6

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VIII (F8) TT1290U FA8_HUMAN Replacement [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haemophilia A
ICD Disease Classification 3B10.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VIII (F8) DTT F8 1.08E-22 0.89 1.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of Spark Therapeutics.