Details of the Drug

General Information of Drug (ID: )

Drug Name

Synonyms

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic thrombocytopenic purpura	3B64.10	Approved	[1]
Chronic liver disease	DB99.0	Phase 3	[1]
Thrombocytopenia	3B64	Phase 2	[1]
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#Ro5 Violations (Lipinski): 1

Molecular Weight (mw)

Logarithm of the Partition Coefficient (xlogp)

Rotatable Bond Count (rotbonds)

Hydrogen Bond Donor Count (hbonddonor)

Hydrogen Bond Acceptor Count (hbondacc)

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thrombopoietin receptor (MPL)	TTIHYA4	TPOR_HUMAN	Agonist	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Idiopathic thrombocytopenic purpura

ICD Disease Classification

3B64.10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Thrombopoietin receptor (MPL)	DTT	MPL	2.61E-06	0.1	0.45

Molecular Expression Atlas (MEA)

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References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022291.
2	Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).