Details of the Drug | DrugMAP

General Information of Drug (ID: DM93BGA)

Drug Name

GSK484

Synonyms

GSK-484; GSK 484

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C27H32ClN5O3
Canonical SMILES: CN1C2=C(C=C(C=C2OC)C(=O)N3CCC(C(C3)N)O)N=C1C4=CC5=CC=CC=C5N4CC6CC6.Cl
InChI: 1S/C27H31N5O3.ClH/c1-30-25-20(11-18(13-24(25)35-2)27(34)31-10-9-23(33)19(28)15-31)29-26(30)22-12-17-5-3-4-6-21(17)32(22)14-16-7-8-16;/h3-6,11-13,16,19,23,33H,7-10,14-15,28H2,1-2H3;1H/t19-,23+;/m0./s1
InChIKey: MULKOGJHUZTANI-ADMBKAPUSA-N

Cross-matching ID

PubChem CID: 86340151
CAS Number: 1652591-81-5
TTD ID: D0Z1RC

References

1	Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11(3):189-91.