Details of the Drug

General Information of Drug (ID: DM95T5Z)

Drug Name

Sapablursen

Indication

Disease Entry	ICD 11	Status	REF
Polycythemia vera	2A20.4	Phase 2	[1]
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Drug Type

Ligand-conjugated antisense

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TMPRSS6 messenger RNA (TMPRSS6 mRNA)	TTNIUKC	TMPS6_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT05143957) A Phase 2a, Randomized, Open-Label Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered to Patients With Phlebotomy Dependent Polycythemia Vera (PD-PV). U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Ionis