Details of the Drug

General Information of Drug (ID: DM95YLX)

• Drug Name: US10071110, Compound cCDV
• Synonyms: SCHEMBL2380283; BDBM275768; US10071110, Compound cCDV; US10071110, Compound Cyclic Cidofovir (cDCV)
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 261.17
  Logarithm of the Partition Coefficient (xlogp); -2.6
  Rotatable Bond Count (rotbonds); 2
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C8H12N3O5P
  IUPAC Name: 4-amino-1-[(2-hydroxy-2-oxo-1,4,2lambda5-dioxaphosphinan-5-yl)methyl]pyrimidin-2-one
  Canonical SMILES: C1C(OCP(=O)(O1)O)CN2C=CC(=NC2=O)N
  InChI: InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)
  InChIKey: YXQUGSXUDFTPLL-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 18914028
  TTD ID: D0N6ZR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytomegalovirus Protease (CMV UL80)	TT5DOVB	SCAF_HCMVA	Inhibitor	[1]

References

• [1] Phosphonate compounds. US10071110.