General Information of Drug (ID: DM9T8OF)

Drug Name
RQ-00000004
Synonyms
PF-03716556; RQ-00000774; RQ-4; Acid pump inhibitor (GERD), Pfizer; Acid pump inhibitor (GERD), RaQualia;Acid pump inhibitor (gastroesophageal reflux), Pfizer; Acid pump inhibitor (gastroesophageal reflux), RaQualia
Indication
Disease Entry ICD 11 Status REF
Gastroesophageal reflux disease DA22.Z Phase 3 [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D05BCU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Gastric H(+)/K(+) ATPase (Proton pump) TTLOKXP ATP4A_HUMAN ; ATP4B_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033657)
2 N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. J Pharmacol Exp Ther. 2009 Feb;328(2):671-9.