Details of the Drug

General Information of Drug (ID: DM9XUYM)

• Drug Name: 2,2-dimethylbenzopyran derivative 2
• Synonyms: PMID26882240-Compound-11
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 368.4
  Logarithm of the Partition Coefficient (xlogp); 4
  Rotatable Bond Count (rotbonds); 6
  Hydrogen Bond Donor Count (hbonddonor); 0
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C22H24O5
  IUPAC Name: 2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethylchromen-6-yl)ethanone
  Canonical SMILES: CC1(C=CC2=C(O1)C=CC(=C2OC)C(=O)CC3=CC(=C(C=C3)OC)OC)C
  InChI: InChI=1S/C22H24O5/c1-22(2)11-10-16-18(27-22)9-7-15(21(16)26-5)17(23)12-14-6-8-19(24-3)20(13-14)25-4/h6-11,13H,12H2,1-5H3
  InChIKey: TZRPLTHVBYHDBJ-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 71453910
  TTD ID: D00GOM

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hypoxia-inducible factor 1 (HIF-1)	TTUX68I	NOUNIPROTAC	Inhibitor	[1]

References

• [1] Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Expert Opin Ther Pat. 2016;26(3):309-22.