Details of the Drug

General Information of Drug (ID: DMAOQO5)

Drug Name

PTC923

Synonyms

sepiapterin; L-Sepiapterin; 17094-01-8; Sepiapterine; CNSA-001; PTC923; Sepiapterin [USAN]; Lopac-S-154; CJQ26KO7HP; (S)-2-Amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one; PTC-923; 2-Amino-6-(S)-lactoyl-7,8-dihydro-4(3H)-pteridinone; 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-3H-pteridin-4-one; 4(3H)-pteridinone, 2-amino-7,8-dihydro-6-((2S)-2-hydroxy-1-oxopropyl)-; UNII-CJQ26KO7HP; 4(3H)-Pteridinone, 2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-; 4(3H)-Pteridinone,2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-; Sepiapterin, solid; SEPIAPTERIN [INN]; Lopac0_001123; 6-lactoyl-7,8-dihydropterin; MLS002153268; SCHEMBL258399; CHEMBL1255653; DTXSID40937902; CHEBI:194527; VPVOXUSPXFPWBN-VKHMYHEASA-N; HMS2234O10; HMS3263B07; Tox21_501123; 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-1H-pteridin-4-one; MFCD00210214; WHO 11848; AKOS022181294; CCG-205198; LP01123; SDCCGSBI-0051091.P002; NCGC00015913-01; NCGC00094391-01; NCGC00094391-02; NCGC00094391-03; NCGC00094391-05; NCGC00261808-01; SMR001230707; HY-112234; CS-0044215; EU-0101123; S-154; C00835; SR-01000075522; Q2271580; SR-01000075522-1; (S)-2-amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(1H)-one; (S)-2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-Pteridinone; 1-(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)-2-hydroxy-1-Propanone; 2-amino-6-[(2S)-2-hydroxypropanoyl]-1,4,7,8-tetrahydropteridin-4-one; 2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-4(1H)Pteridinone; S(-)-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridione; S-(-)-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridinone; 2-AMINO-7,8-DIHYDRO-6-((2S)-2-HYDROXY-1-OXOPROPYL)-4(3H)-PTERIDINONE; 4(1H)-Pteridinone, 2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-, (S)-

Indication

Disease Entry	ICD 11	Status	REF
Phenylketonuria	5C50.0	Phase 3	[1]
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Drug Type

Small molecule

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C9H11N5O3
Canonical SMILES: CC(C(=O)C1=NC2=C(NC1)N=C(NC2=O)N)O
InChI: InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17)/t3-/m0/s1
InChIKey: VPVOXUSPXFPWBN-VKHMYHEASA-N

Cross-matching ID

PubChem CID: 135398579
TTD ID: DDU0O9

References

1	ClinicalTrials.gov (NCT05099640) A Phase 3 Study of PTC923 in Subjects With Phenylketonuria. U.S.National Institutes of Health.