Details of the Drug

General Information of Drug (ID: DMAXB8T)

Drug Name
ISIS 12882
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
GTCCCCACCGCCACTCCTGG
Cross-matching ID
TTD ID
D0S3AR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ERBB2 messenger RNA (HER2 mRNA) TTR5TV4 ERBB2_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ERBB2 messenger RNA (HER2 mRNA) DTT ERBB2 3.50E-77 0.49 1.12
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 5,968,748, Antisense oligonucleotide modulation of human HER-2 expression.