Details of the Drug

General Information of Drug (ID: DMB7CPG)

Drug Name

Elsiglutide

Synonyms

Tide ZP-1846; ZP-1846; GLP-2 analog (chemotherapy-induced diarrhoea), Zealand Pharma

Indication

Disease Entry	ICD 11	Status	REF
Diarrhea	ME05.1	Phase 2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon-like peptide 2 receptor (GLP2R)	TT1YWO5	GLP2R_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Diarrhea

ICD Disease Classification

ME05.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glucagon-like peptide 2 receptor (GLP2R)	DTT	GLP2R	6.12E-01	0.06	0.3

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT01543451) Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea. U.S. National Institutes of Health.
2	Poster Abstracts. Volume 10, Issue Supplement S8, pages 126-209, December 2014.