Details of the Drug

General Information of Drug (ID: DMBAHYO)

Drug Name

Pyrimidine derivative 6

Synonyms

PMID28621580-Compound-US20160096837c61

Indication

Disease Entry	ICD 11	Status	REF
Blood vessel proliferative disorder	BE2Z	Patented	[1]
Fibrosis	GA14-GC01	Patented	[1]
Neurodegenerative disorder	8A20-8A23	Patented	[2]
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Drug Type

Small molecular drug

Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor A (VEGFA)	TTOHSBA	VEGFA_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Blood vessel proliferative disorder

ICD Disease Classification

BE2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor A (VEGFA)	DTT	VEGFA	3.61E-01	0.15	0.47

Molecular Expression Atlas (MEA)

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References

1	VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Sep;27(9):987-1004.
2	Novel NF-B inhibitors: a patent review (2011 - 2014).Expert Opin Ther Pat. 2015 Mar;25(3):319-34.