Details of the Drug

General Information of Drug (ID: DMBZ68C)

Drug Name
MALP-2S
Indication
Disease Entry ICD 11 Status REF
Pancreatic cancer 2C10 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0K3SM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Toll-like receptor 2 (TLR2) TTY7ZHS TLR2_HUMAN Modulator [2]
Toll-like receptor 6 (TLR6) TTWRI8V TLR6_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Pancreatic cancer
ICD Disease Classification 2C10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Toll-like receptor 2 (TLR2) DTT TLR2 1.75E-01 -0.48 -0.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: a phase ... Br J Cancer. 2007 Sep 3;97(5):598-604.
2 Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2. Microbes Infect. 2011 Apr;13(4):350-8.