Details of the Drug

General Information of Drug (ID: DMCFR8U)

Drug Name

CBLB-612

Synonyms

Recombinant flagellin proteins (injectable, radiation induced bone marrow deficiency), Cleveland BioLabs; CBLB-600 series (injectable, radiation sickness), Cleveland BioLabs

Indication

Disease Entry	ICD 11	Status	REF
Radiation syndrome	NF00	Investigative	[1]
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Cross-matching ID

TTD ID: D04UYT

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Toll-like receptor 2 (TLR2)	TTY7ZHS	TLR2_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Radiation syndrome

ICD Disease Classification

NF00

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 2 (TLR2)	DTT	TLR2	1.75E-01	-0.48	-0.45

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1752).