Details of the Drug

General Information of Drug (ID: DMCGEDY)

Drug Name

GW4064

Synonyms

GW 4064; 278779-30-9; GW4064; GW-4064; UNII-SR225WUZ0H; (E)-3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid; GW-4064X; 1089660-72-9; SR225WUZ0H; CHEMBL318457; CHEBI:79997; Benzoic acid, 3-(2-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl)methoxy)phenyl)ethenyl)-; 3-[(E)-2-(2-Chloro-4-{[3-(2,6-Dichlorophenyl)-5-(1-Methylethyl)isoxazol-4-Yl]methoxy}phenyl)ethenyl]benzoic Acid

Indication

Disease Entry	ICD 11	Status	REF
Hepatic fibrosis	DB93.0	Preclinical	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C28H22Cl3NO4
Canonical SMILES: CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)C=CC4=CC(=CC=C4)C(=O)O)Cl
InChI: 1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)/b10-9+
InChIKey: BYTNEISLBIENSA-MDZDMXLPSA-N

Cross-matching ID

PubChem CID: 9893571
ChEBI ID: CHEBI:79997
CAS Number: 278779-30-9
TTD ID: D00UQF

References

1	Drugs and Targets in Fibrosis. Front Pharmacol. 2017 Nov 23;8:855.