Details of the Drug

General Information of Drug (ID: DMCT4BA)

Drug Name
DMUC-5754A
Indication
Disease Entry ICD 11 Status REF
Fallopian tube cancer 2C74 Phase 1 [1]
Ovarian cancer 2C73 Phase 1 [1]
Peritoneal cancer 2C51.Z Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D04ZIZ
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ovarian carcinoma antigen CA125 (MUC16) TTC1PS3 MUC16_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01335958) Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer. U.S. National Institutes of Health.
2 Maturing antibody-drug conjugate pipeline hits 30. Nat Rev Drug Discov. 2013 May;12(5):329-32.