Details of the Drug

General Information of Drug (ID: DMCT8EY)

Drug Name
Cenderitide
Indication
Disease Entry ICD 11 Status REF
Heart disease BA41-BA42 Phase 2 [1]
Heart failure BD10-BD13 Phase 1 [2]
Cross-matching ID
PubChem CID
155817506
DrugBank ID
DB11777
TTD ID
D0OK3O
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Atrial natriuretic peptide receptor A (NPR1) TTJME02 ANPRA_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressurein a proof-of-concept study in patients with chronic heart failure. BMC Pharmacol. 2011; 11(Suppl 1): P18.
2 2011 Pipeline of Nile Therapeutics.