Details of the Drug

General Information of Drug (ID: DMCUGNY)

Drug Name

Tetomilast

Synonyms

Tetomilast; 145739-56-6; 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinic acid; OPC-6535; UNII-S6RXB5KF56; S6RXB5KF56; 2-(3,4-Diethoxyphenyl)-4-(2-carboxy-6-pyridyl)thiazole; 2-Pyridinecarboxylicacid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-; 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid; Tetomilast [INN]; 6-(2-(3,4-Diethoxyphenyl)-1,3-thiazol-4-yl)pyridine-2-carboxylic acid; OPC 6535; ACMC-1BW9F; AC1MHG07; SCHEMBL436663; GTPL9877; CHEMBL332750; CTK0H7037; OPC6535; DTXSID00163149

Indication

Disease Entry	ICD 11	Status	REF
Chronic obstructive pulmonary disease	CA22	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C19H18N2O4S
Canonical SMILES: CCOC1=C(C=C(C=C1)C2=NC(=CS2)C3=NC(=CC=C3)C(=O)O)OCC
InChI: 1S/C19H18N2O4S/c1-3-24-16-9-8-12(10-17(16)25-4-2)18-21-15(11-26-18)13-6-5-7-14(20-13)19(22)23/h5-11H,3-4H2,1-2H3,(H,22,23)
InChIKey: XDBHURGONHZNJF-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 3025803
CAS Number: 145739-56-6
TTD ID: D0T6IM

References

1	ClinicalTrials.gov (NCT00874497) Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema. U.S. National Institutes of Health.