Details of the Drug

General Information of Drug (ID: DMDKWA3)

Drug Name

Vx-001

Synonyms

HTERT572Y peptide vaccine (cancer), Vaxon; HLA-A2 monopeptide vaccine (cancer), Vaxon; TERT572 + TERT572Y peptide (cancer), Vaxon

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Phase 2	[1]
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Drug Type

Vaccine

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Telomerase reverse transcriptase (TERT)	TTUJFD0	TERT_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Breast cancer

ICD Disease Classification

2C60-2C65

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Telomerase reverse transcriptase (TERT)	DTT	TERT	8.59E-10	-0.08	-0.33

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT01935154) Efficacy Study of Vx001 Vaccine in NSCLC Patients. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Vaxon-biotech.