Details of the Drug

General Information of Drug (ID: DME7V7X)

Drug Name

OZ-439

Synonyms

Oral quick release synthetic trioxolane (Plasmodium infections), MMV/UNMC/STPI/Monash University

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 2	[1]
------------------------------------------------------------------------------------

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C28H39NO5
Canonical SMILES: C1CC2(CCC1C3=CC=C(C=C3)OCCN4CCOCC4)OC5(C6CC7CC(C6)CC5C7)OO2
InChI: 1S/C28H39NO5/c1-3-26(31-14-11-29-9-12-30-13-10-29)4-2-22(1)23-5-7-27(8-6-23)32-28(34-33-27)24-16-20-15-21(18-24)19-25(28)17-20/h1-4,20-21,23-25H,5-19H2
InChIKey: XLCNVWUKICLURR-UHFFFAOYSA-N

Cross-matching ID

References

1	ClinicalTrials.gov (NCT02083380) Phase IIb Study to Investigate the Efficacy of OZ439 & Piperaquine Phosphate Co-administered to Adults & Children With Uncomplicated Plasmodium Falciparum.. U.S. National Institutes of Health.