Details of the Drug

General Information of Drug (ID: DME9V0I)

Drug Name

RNAPc2

Synonyms

RAcAPc2; Recombinant nematode anticoagulant protein, Dendreon; Recombinant nematode anticoagulant protein, Nuvelo

Indication

Disease Entry	ICD 11	Status	REF
Colorectal cancer	2B91.Z	Discontinued in Phase 2	[1]
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ADMET Property

Half-life: The concentration or amount of drug in body reduced by one-half in more than 50 hours [2]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Colorectal cancer

ICD Disease Classification

2B91.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor VII (F7)	DTT	F7	2.52E-01	-0.03	-0.19

Molecular Expression Atlas (MEA)

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006762)
2	Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
3	rNAPc2 inhibits colorectal cancer in mice through tissue factor. Clin Cancer Res. 2009 Jan 1;15(1):208-16.