Details of the Drug

General Information of Drug (ID: DMEJYV4)

Drug Name

(S)-4-(Ethylsulfonyl)benzoylalanine

Synonyms

S-ESBA

Indication

Disease Entry	ICD 11	Status	REF
Cognitive impairment	6D71	Preclinical	[1]
Schizophrenia	6A20	Preclinical	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Kynurenine oxoglutarate transaminase II (AADAT)	TTT3IXG	AADAT_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nat Rev Drug Discov. 2019 May;18(5):379-401.
2	Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum. Neuroscience. 2009 Mar 3;159(1):196-203.