Details of the Drug

General Information of Drug (ID: DMELNA8)

Drug Name

TGN-1412

Synonyms

SuperMAB; CD28-SuperMAB; Superagonistic monoclonal antibodies, TeGenero

Indication

Disease Entry	ICD 11	Status	REF
Autoimmune diabetes	5A10	Discontinued in Phase 1	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cell-specific surface glycoprotein CD28 (CD28)	TTQ13FT	CD28_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020365)
2	TGN1412: From Discovery to Disaster. J Young Pharm. 2010 Jul-Sep; 2(3): 332-336.