Details of the Drug | DrugMAP

General Information of Drug (ID: DMELUQV)

Drug Name

GS-8374

Synonyms

HIV protease inhibitor (diethylphosphonate motif), Gilead

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Investigative	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C33H49N2O12PS
Canonical SMILES: CCOP(=O)(COC1=CC=C(C=C1)CC(C(CN(CC(C)C)S(=O)(=O)C2=CC=C(C=C2)OC)O)NC(=O)OC3COC4C3CCO4)OCC
InChI: 1S/C33H49N2O12PS/c1-6-45-48(38,46-7-2)22-44-26-10-8-24(9-11-26)18-29(34-33(37)47-31-21-43-32-28(31)16-17-42-32)30(36)20-35(19-23(3)4)49(39,40)27-14-12-25(41-5)13-15-27/h8-15,23,28-32,36H,6-7,16-22H2,1-5H3,(H,34,37)/t28-,29-,30+,31-,32+/m0/s1
InChIKey: FCLYPCIMVVLLRN-FXSYQQGGSA-N

Cross-matching ID

PubChem CID: 12004117
TTD ID: D00SKS

References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.