Details of the Drug | DrugMAP

General Information of Drug (ID: DMEVGR6)

Drug Name	US10149841, Compound 1
Synonyms	SCHEMBL19808953; US10149841, Compound 1; BDBM306795
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight (mw)			288.25
	Logarithm of the Partition Coefficient (xlogp)			1.8
	Rotatable Bond Count (rotbonds)			5
	Hydrogen Bond Donor Count (hbonddonor)			3
	Hydrogen Bond Acceptor Count (hbondacc)			6
Chemical Identifiers	Formula C14H12N2O5 IUPAC Name 2-[(3-hydroxy-5-phenoxypyridine-2-carbonyl)amino]acetic acid Canonical SMILES C1=CC=C(C=C1)OC2=CC(=C(N=C2)C(=O)NCC(=O)O)O InChI InChI=1S/C14H12N2O5/c17-11-6-10(21-9-4-2-1-3-5-9)7-15-13(11)14(20)16-8-12(18)19/h1-7,17H,8H2,(H,16,20)(H,18,19) InChIKey SUWPOWJCFOLJFD-UHFFFAOYSA-N
Cross-matching ID	PubChem CID 134204800 TTD ID D0JR2Q

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HIF-prolyl hydroxylase 2 (HPH-2)	TT9ISBX	EGLN1_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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References

1	Compound of 3-hydroxyl pyridine, preparation method thereof and pharmaceutical use thereof. US10149841.