Details of the Drug

General Information of Drug (ID: DMEY1AP)

Drug Name
HSDB-3165
Synonyms
D-Gluconic acid potassium salt; Potassium gluconate; D-Gluconic acid, potassium salt; Gluconic acid potassium salt; Gluconic acid, monopotassium salt; Gluconsan; Gluconsan K; Kalium Gluconate; Kalium-beta; Kaon elixir; Katorin; Monopotassium D-gluconate; Potalium; Potasoral; Potassium D-gluconate; Potassuril; Sirokal; 12H3K5QKN9; 299-27-4; D-Gluconic acid, monopotassium salt; EINECS 206-074-2; HSDB 3165; K-Iao; KOK; Kaon; MFCD00064211; UNII-12H3K5QKN9; potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 234.25
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 5
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 7
ADMET Property
Elimination
90% of potassium is eliminated via the kidneys. A small amount is eliminated in feces and sweat [1]
Chemical Identifiers
Formula
C6H11KO7
IUPAC Name
potassium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
Canonical SMILES
C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[K+]
InChI
HLCFGWHYROZGBI-JJKGCWMISA-M
InChIKey
1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
Cross-matching ID
PubChem CID
16760467
ChEBI ID
CHEBI:32032
CAS Number
299-27-4
DrugBank ID
DB13620
INTEDE ID
DR1317

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Sodium/potassium-transporting ATPase gamma (FXYD2)
Main DME 		DEULQ45 ATNG_HUMAN Substrate [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 NIH Toxnet, Potassium
2 Rare mutations in renal sodium and potassium transporter genes exhibit impaired transport function. Curr Opin Nephrol Hypertens. 2014 Jan;23(1):1-8.