Details of the Drug

General Information of Drug (ID: DMFIP0D)

• Drug Name: Imidazo[1,5-a]pyridine derivative 1
• Synonyms: PMID29473428-Compound-12
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 264.75
  Logarithm of the Partition Coefficient (xlogp); 4
  Rotatable Bond Count (rotbonds); 2
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C14H17ClN2O
  IUPAC Name: (S)-(7-chloroimidazo[1,5-a]pyridin-5-yl)-cyclohexylmethanol
  Canonical SMILES: C1CCC(CC1)[C@@H](C2=CC(=CC3=CN=CN23)Cl)O
  InChI: InChI=1S/C14H17ClN2O/c15-11-6-12-8-16-9-17(12)13(7-11)14(18)10-4-2-1-3-5-10/h6-10,14,18H,1-5H2/t14-/m0/s1
  InChIKey: AVJCRIIDMDBAQC-AWEZNQCLSA-N
• Cross-matching ID:
  PubChem CID: 122604981
  TTD ID: D0ZV6F

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Indoleamine 2,3-dioxygenase 1 (IDO1)	TTZJYKH	I23O1_HUMAN	Inhibitor	[1]

References

• [1] A patent review of IDO1 inhibitors for cancer.Expert Opin Ther Pat. 2018 Apr;28(4):317-330.