Details of the Drug

General Information of Drug (ID: DMGF2PU)

Drug Name

BNT411

Indication

Disease Entry	ICD 11	Status	REF
Small-cell lung cancer	2C25.Y	Phase 1/2	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Small-cell lung cancer

ICD Disease Classification

2C25.Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 7 (TLR7)	DTT	TLR7	3.32E-25	0.44	0.88

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT04101357) Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of BioNTech.