Details of the Drug

General Information of Drug (ID: DMGLSPC)

Drug Name
Salicylhydroxamic acid
Synonyms
Salicylhydroxamic acid; N,2-Dihydroxybenzamide; 89-73-6; 2-Hydroxybenzohydroxamic acid; Salicylohydroxamic acid; SHAM; Salicylohydroximic acid; Benzamide, N,2-dihydroxy-; 2-Hydroxybenzhydroxamic acid; O-Hydroxybenzohydroxamic acid; SalicylhydroxaMicacid; SHA; 2,N-Dihydroxy-benzamide; NSC 5088; NSC 193440; Saliaylhydroxamic acid; UNII-8Q07182D0T; 2-hydroxybenzenecarbohydroxamic acid; Salicylic Hydroxamic Acid; EINECS 201-934-3; Salicylhydroxamic acid, 99%; MLS000069410; CHEMBL309339; CHEBI:45615; NSC5088
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 153.14
Logarithm of the Partition Coefficient (xlogp) 0.9
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C7H7NO3
IUPAC Name
N,2-dihydroxybenzamide
Canonical SMILES
C1=CC=C(C(=C1)C(=O)NO)O
InChI
InChI=1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)
InChIKey
HBROZNQEVUILML-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
66644
ChEBI ID
CHEBI:45615
CAS Number
89-73-6
DrugBank ID
DB03819
TTD ID
D0H6QL
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) TT3PQ2Y PYRD_PLAF7 Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Effects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenase. Antimicrob Agents Chemother. 1995 Feb;39(2):325-8.