Details of the Drug

General Information of Drug (ID: DMGLVBI)

Drug Name

JTT-302

Synonyms

CETP inhibitor (oral, dyslipidemia), Japan Tobacco

Indication

Disease Entry	ICD 11	Status	REF
Lipid metabolism disorder	5C52.Z	Phase 2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cholesteryl ester transfer protein (CETP)	TTFQAYR	CETP_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Lipid metabolism disorder

ICD Disease Classification

5C52.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Cholesteryl ester transfer protein (CETP)	DTT	CETP	8.86E-01	-0.1	-0.6

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT00748852) Safety Study of JTT-302 in Subjects With Low HDL-C Levels. U.S. National Institutes of Health.
2	The dyslipidaemia market. Nat Rev Drug Discov. 2014 Nov;13(11):807-8.