Details of the Drug

General Information of Drug (ID: DMGPR1C)

Drug Name
CART-EGFRvIII T cells
Indication
Disease Entry ICD 11 Status REF
Recurrent glioblastoma 2A00.00 Phase 1 [1]
Glioma 2A00.0 Clinical trial [2]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D0B5PV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor receptor variant III (EGFR vIII) TTZ6B2I EGFR_HUMAN CAR-T-Cell-Therapy [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03726515) CART-EGFRvIII + Pembrolizumab in GBM
2 ClinicalTrials.gov (NCT02209376) Autologous T Cells Redirected to EGFRVIII-With a Chimeric Antigen Receptor in Patients With EGFRVIII+ Glioblastoma