Details of the Drug

General Information of Drug (ID: DMGUQMJ)

Drug Name

Delpazolid

Synonyms

LCB01-0371; 1219707-39-7; UNII-43EP6XV33E; LCB-01-0371; LCB-010371; 43EP6XV33E; (5R)-3-[3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one; (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)oxazolidin-2-one; Delpazolid (LCB01-0371); CHEMBL1673408; SCHEMBL11969210; GTPL10999; BCP25650; EX-A1715; ACN-053047; DB13077; SB18949; LCB-01,0371; 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)-; HY-100180; CS-0018175; Q27258646; (R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

Indication

Disease Entry	ICD 11	Status	REF
Pulmonary tuberculosis	1B10.Z	Phase 2	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C14H17FN4O3
Canonical SMILES: CN1CCN(C=N1)C2=C(C=C(C=C2)N3CC(OC3=O)CO)F
InChI: 1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1
InChIKey: QLUWQAFDTNAYPN-LLVKDONJSA-N

Cross-matching ID

PubChem CID: 44205191
CAS Number: 1219707-39-7
TTD ID: D0V3FM

References

1	ClinicalTrials.gov (NCT02836483) A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK. U.S. National Institutes of Health.