Details of the Drug

General Information of Drug (ID: DMHFGMQ)

Drug Name

2-(pyridin-2-yl)-1H-imidazo[4,5-c]pyridine

Synonyms

CHEMBL202826; 14060-62-9; 2-(2-Pyridinyl)-1H-imidazo[4,5-c]pyridine; AC1LJB5G; 2-(pyridin-2-yl)-1H-imidazo[4,5-c]pyridine; 3H-Imidazo[4,5-c]pyridine, 2-(2-pyridinyl)-; Oprea1_672867; SCHEMBL11397558; 2-pyridylimidazo[4,5-c]pyridine; MolPort-002-623-631; ZINC5819379; BDBM50180747; STL346357; AKOS022141602; AKOS012572462; MCULE-6118149650; NCGC00375714-01; NCGC00375714-02; 2-pyridin-2-yl-3H-imidazo[4,5-c]pyridine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

196.21

Logarithm of the Partition Coefficient (xlogp)

1

Rotatable Bond Count (rotbonds)

1

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C11H8N4
IUPAC Name: 2-pyridin-2-yl-3H-imidazo[4,5-c]pyridine
Canonical SMILES: C1=CC=NC(=C1)C2=NC3=C(N2)C=NC=C3
InChI: InChI=1S/C11H8N4/c1-2-5-13-9(3-1)11-14-8-4-6-12-7-10(8)15-11/h1-7H,(H,14,15)
InChIKey: RCQLXXHLXWNHOU-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 947740
TTD ID: D08AXA

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Methionine aminopeptidase 2 (METAP2)	TTZL0OI	MAP2_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors, Bioorg. Med. Chem. Lett. 20(14):4038-4044 (2010).