Details of the Drug

General Information of Drug (ID: DMHNPSO)

• Drug Name: 1190312-92-5
• Synonyms: 3-chloro-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid; 1190312-92-5; 3-CHLORO-4-AZAINDOLE-7-CARBOXYLIC ACID; SCHEMBL16157363; US10174026, Example 1; UAFNSWUBMGTOQA-UHFFFAOYSA-N; BDBM320361; ZINC44713035; 3-chloro-1H-pyrrolo[3,2-b] pyridine-7-carboxylic acid
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 196.59
  Logarithm of the Partition Coefficient (xlogp); 1.2
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C8H5ClN2O2
  IUPAC Name: 3-chloro-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
  Canonical SMILES: C1=CN=C2C(=CNC2=C1C(=O)O)Cl
  InChI: InChI=1S/C8H5ClN2O2/c9-5-3-11-6-4(8(12)13)1-2-10-7(5)6/h1-3,11H,(H,12,13)
  InChIKey: UAFNSWUBMGTOQA-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 53412620
  TTD ID: D0ZJ0Z

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lysine-specific demethylase 5A (KDM5A)	TTIG67W	KDM5A_HUMAN	Inhibitor	[1]

References

• [1] Histone demethylase inhibitors. US10174026.