Details of the Drug

General Information of Drug (ID: DMHZUF8)

Drug Name
AGN-208397
Indication
Disease Entry ICD 11 Status REF
Retina venous occlusion 9B74.1 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0G4AJ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Erbb2 tyrosine kinase receptor (HER2) TT6EO5L ERBB2_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Retina venous occlusion
ICD Disease Classification 9B74.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Erbb2 tyrosine kinase receptor (HER2) DTT ERBB2 5.67E-03 -1.26 -2.05
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01027650) Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO). U.S. National Institutes of Health.
2 New hope for dry AMD. Nat Rev Drug Discov. 2013 Jul;12(7):501-2.