Details of the Drug

General Information of Drug (ID: DMI9Q6L)

Drug Name
Tefinostat
Synonyms CHR-2845; CHR-2847; CHR-2875; Small molecule inhibitor (hematological malignancies), Chroma
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C28H37N3O5
Canonical SMILES
C1CCC(C1)OC(=O)C(C2=CC=CC=C2)NCC3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO
InChI
1S/C28H37N3O5/c32-25(14-6-1-2-7-15-26(33)31-35)30-23-18-16-21(17-19-23)20-29-27(22-10-4-3-5-11-22)28(34)36-24-12-8-9-13-24/h3-5,10-11,16-19,24,27,29,35H,1-2,6-9,12-15,20H2,(H,30,32)(H,31,33)/t27-/m0/s1
InChIKey
GLNWREBYRLDPQP-MHZLTWQESA-N
Cross-matching ID
PubChem CID
15940949
CAS Number
914382-60-8
TTD ID
D09TLE

References

1 ClinicalTrials.gov (NCT00820508) Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid Malignancies. U.S. National Institutes of Health.