Details of the Drug

General Information of Drug (ID: DMIBHP5)

• Drug Name: 5-aminoquinolin-8-ol
• Synonyms: 5-aminoquinolin-8-ol; 13207-66-4; 5-Amino-8-hydroxyquinoline; 8-Quinolinol, 5-amino-; 5-Amino-8-quinolinol; 5-Amino-quinolin-8-ol; 5-azanylquinolin-8-ol; YDEUKNRKEYICTH-UHFFFAOYSA-N; AS-0308-225; 5-aminoquinoline-8-ol; AC1L9ASV; 5-Amino-8-quinolinol #; SCHEMBL688655; 5'-amino-8'-hydroxyquinoline; CHEMBL449298; AMOT0046; AC1Q523Z; cid_416002; BDBM32142; CTK0H3311; DTXSID20328975; MolPort-000-000-986; ZINC120515; ALBB-024871; 5-Amino-8-hydroxyquinoline HClsalt; ANW-61190; 5928AA; BBL028356; STK737829; SBB005680; AKOS000111586

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 160.17
  Logarithm of the Partition Coefficient (xlogp); 1.6
  Rotatable Bond Count (rotbonds); 0
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C9H8N2O
  IUPAC Name: 5-aminoquinolin-8-ol
  Canonical SMILES: C1=CC2=C(C=CC(=C2N=C1)O)N
  InChI: InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2
  InChIKey: YDEUKNRKEYICTH-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 416002
  CAS Number: 13207-66-4
  TTD ID: D0W3ON

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Indoleamine 2,3-dioxygenase 1 (IDO1)	TTZJYKH	I23O1_HUMAN	Inhibitor	[1]

References

• [1] Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem. 2010 Feb 11;53(3):1172-89.