Details of the Drug

General Information of Drug (ID: DMIRCF1)

Drug Name

QR1123

Synonyms

ION357

Indication

Disease Entry	ICD 11	Status	REF
Retinitis pigmentosa	9B70	Phase 1/2	[1]
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Drug Type

Antisense oligonucleotide

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Rhodopsin P23H mutant messenger RNA (RHO P23H mRNA)	TTG6VJM	OPSD_HUMAN	Not Available	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT04123626) A Prospective First-In-Human Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa (adRP) Due to the P23H Mutation in the RHO Gene. U.S.National Institutes of Health.