Details of the Drug

General Information of Drug (ID: DMJI1EA)

Drug Name

BND-001

Synonyms

NiK-001; NiK-10001; NiK-10034; NiK-18862; Nik-21273; ORL-1 antagonists (CNS disorders); ORL-1 antagonists (CNS disorders), Brane; Opioid receptor like-1 antagonists (CNS disorders), NiKem Research

Indication

Disease Entry	ICD 11	Status	REF
Central nervous system disease	8A04-8D87	Investigative	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

TTD ID: D0Y5MF

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nociceptin receptor (OPRL1)	TTNT7K8	OPRX_HUMAN	Antagonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Central nervous system disease

ICD Disease Classification

8A04-8D87

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nociceptin receptor (OPRL1)	DTT	OPRL1	1.75E-01	0.05	0.25

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 320).