Details of the Drug

General Information of Drug (ID: DMKETFV)

Drug Name

SMER3

Synonyms

67200-34-4; SMER 3; 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one; 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one; SMER-3; C11H4N4O2; LSM-42773; 9H-Indeno-[1,2-e]-[1,2,5]-oxadiazolo-[3,4-b]-pyrazin-9-one; indeno[2,3-b]1,2,5-oxadiazolo[3,4-e]pyrazin-5-one; 2-Oxa-1,3,4,10-tetraaza-cyclopenta[b]fluoren-9-one; SMER3(SMER 3); Oprea1_175199; Oprea1_783821; SCHEMBL7984580; CHEMBL3589013; ZINC27763; AOB5567; DTXSID40340952; CHEBI:131171; BDBM188214; HMS1607O01; BCP14360; 2188AH; MFCD00451458; SBB000632; STK120842; SMER3, >=98% (HPLC); AKOS000479457; MCULE-1070513713; AS-55891; ST000573; DB-073845; FT-0701471; Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one; Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one,; US9073941, 28; US9073941, 30; SR-01000388225; SR-01000388225-1; Q27224946; 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one #

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Preclinical	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C11H4N4O2
Canonical SMILES: C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
InChI: 1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
InChIKey: SFSSAKVWCKFRHE-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 568763
ChEBI ID: CHEBI:131171
CAS Number: 67200-34-4
TTD ID: DHD79B

References

1	Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.