Details of the Drug

General Information of Drug (ID: DMKSQY1)

Drug Name

Azelaic bishydroxamic acid

Synonyms

Azelaic bishydroxamic acid; 18992-11-5; Azelaic bis(hydroxamic acid); Nonanedihydroximic acid; N,N'-dihydroxynonanediamide; Azelaic bis hydroxamic acid; AC1L22XV; SCHEMBL4741072; CHEMBL495390; Nonanediamide, N,N'-dihydroxy-; DTXSID30172421; ZINC5178518; NSC611775

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

218.25

Logarithm of the Partition Coefficient (xlogp)

0.1

Rotatable Bond Count (rotbonds)

8

Hydrogen Bond Donor Count (hbonddonor)

4

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C9H18N2O4
IUPAC Name: N,N'-dihydroxynonanediamide
Canonical SMILES: C(CCCC(=O)NO)CCCC(=O)NO
InChI: InChI=1S/C9H18N2O4/c12-8(10-14)6-4-2-1-3-5-7-9(13)11-15/h14-15H,1-7H2,(H,10,12)(H,11,13)
InChIKey: VBJZDMOTYJEHEP-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 65268
CAS Number: 18992-11-5
TTD ID: D0PQ5T

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Histone deacetylase (HDAC)	TTBH0VX	NOUNIPROTAC	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov. 2006 Sep;5(9):769-84.