Details of the Drug

General Information of Drug (ID: DMKV9EZ)

Drug Name

2,3-Dimethylnaphtho[2,3-f]quinoxaline-7,12-dione

Synonyms

2,3-Dimethylnaphtho[2,3-f]quinoxaline-7,12-dione; 89986-91-4; Naphtho[2,3-f]quinoxaline-7,12-dione, 2,3-dimethyl-; ACMC-20lsfz; SCHEMBL3505034; CHEMBL604342; CTK2I7956; DTXSID80658048

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

288.3

Logarithm of the Partition Coefficient (xlogp)

3

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C18H12N2O2
IUPAC Name: 2,3-dimethylnaphtho[3,2-f]quinoxaline-7,12-dione
Canonical SMILES: CC1=C(N=C2C(=N1)C=CC3=C2C(=O)C4=CC=CC=C4C3=O)C
InChI: InChI=1S/C18H12N2O2/c1-9-10(2)20-16-14(19-9)8-7-13-15(16)18(22)12-6-4-3-5-11(12)17(13)21/h3-8H,1-2H3
InChIKey: WDHCRURNPCZZII-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 44251290
CAS Number: 89986-91-4
TTD ID: D04LTV

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TERT messenger RNA (TERT mRNA)	TTQY2EJ	TERT_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28.